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Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome
The hedgehog (Hh) signaling pathway is considered to be a major signal transduction pathway during embryonic development but it usually shuts down after birth. Aberrant Shh activation during adulthood leads to neoplastic growth. Basal cell carcinoma (BCC) of the skin is driven by this pathway. Here,...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167483/ https://ncbi.nlm.nih.gov/pubmed/25172843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1666 |
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