Loading...

Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome

The hedgehog (Hh) signaling pathway is considered to be a major signal transduction pathway during embryonic development but it usually shuts down after birth. Aberrant Shh activation during adulthood leads to neoplastic growth. Basal cell carcinoma (BCC) of the skin is driven by this pathway. Here,...

Full description

Saved in:
Bibliographic Details
Main Authors: Athar, Mohammad, Li, Changzhao, Kim, Arianna L., Spiegelman, Vladimir S, Bickers, David R.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167483/
https://ncbi.nlm.nih.gov/pubmed/25172843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1666
Tags: Add Tag
No Tags, Be the first to tag this record!