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Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome

The hedgehog (Hh) signaling pathway is considered to be a major signal transduction pathway during embryonic development but it usually shuts down after birth. Aberrant Shh activation during adulthood leads to neoplastic growth. Basal cell carcinoma (BCC) of the skin is driven by this pathway. Here,...

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Autors principals: Athar, Mohammad, Li, Changzhao, Kim, Arianna L., Spiegelman, Vladimir S, Bickers, David R.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167483/
https://ncbi.nlm.nih.gov/pubmed/25172843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1666
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