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Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog
Holoprosencephaly (HPE) is a clinically heterogeneous developmental anomaly affecting the CNS and face, in which the embryonic forebrain fails to divide into distinct halves. Numerous genetic loci and environmental factors are implicated in HPE, but mutation in the sonic hedgehog (Shh) gene is an es...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868789/ https://ncbi.nlm.nih.gov/pubmed/17525797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32032 |
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