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Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function

Holoprosencephaly is a heterogeneous developmental malformation of the central nervous system characterized by impaired forebrain cleavage, midline facial anomalies and wide phenotypic variation. Indeed, microforms represent the mildest manifestation, associated with facial anomalies but an intact c...

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Autors principals: Seppala, Maisa, Xavier, Guilherme M., Fan, Chen-Ming, Cobourne, Martyn T.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133726/
https://ncbi.nlm.nih.gov/pubmed/25063195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147989
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