On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF

BACKGROUND: The Dbl-family of guanine nucleotide exchange factors (GEFs) activate the cytosolic GTPases of the Rho family by enhancing the rate of exchange of GTP for GDP on the cognate GTPase. This catalytic activity resides in the DH (Dbl-homology) domain, but typically GEFs are multidomain protei...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zheng, Meiying, Cierpicki, Tomasz, Momotani, Ko, Artamonov, Mykhaylo V, Derewenda, Urszula, Bushweller, John H, Somlyo, Avril V, Derewenda, Zygmunt S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695464/
https://ncbi.nlm.nih.gov/pubmed/19460155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-9-36
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados