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Agonist-induced Ca(2+) Sensitization in Smooth Muscle: REDUNDANCY OF RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS (RhoGEFs) AND RESPONSE KINETICS, A CAGED COMPOUND STUDY
Many agonists, acting through G-protein-coupled receptors and Gα subunits of the heterotrimeric G-proteins, induce contraction of smooth muscle through an increase of [Ca(2+)](i) as well as activation of the RhoA/RhoA-activated kinase pathway that amplifies the contractile force, a phenomenon known...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837142/ https://ncbi.nlm.nih.gov/pubmed/24106280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514596 |
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