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Thermodynamic analysis of acetylation-dependent Pb1 bromodomain—histone H3 interactions

An acetyl-histone peptide library was used to determine the thermodynamic parameters that define acetylation-dependent bromodomain—histone interactions. Bromodomains interact with histones by binding acetylated lysines. The bromodomain used in this study, BrD3, is derived from the polybromo-1 protei...

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Autori principali: Thompson, Martin, Chandrasekaran, Renu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693409/
https://ncbi.nlm.nih.gov/pubmed/18191465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.12.008
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