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HISTONE H3-K56 ACETYLATION IS CATALYZED BY HISTONE CHAPERONE-DEPENDENT COMPLEXES
Acetylation of histone H3 on lysine 56 occurs during mitotic and meiotic S phase in fungal species. This acetylation blocks a direct electrostatic interaction between histone H3 and nucleosomal DNA, and the absence of this modification is associated with extreme sensitivity to genotoxic agents. We s...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1853276/ https://ncbi.nlm.nih.gov/pubmed/17320445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.02.006 |
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