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Thermodynamic analysis of acetylation-dependent Pb1 bromodomain—histone H3 interactions
An acetyl-histone peptide library was used to determine the thermodynamic parameters that define acetylation-dependent bromodomain—histone interactions. Bromodomains interact with histones by binding acetylated lysines. The bromodomain used in this study, BrD3, is derived from the polybromo-1 protei...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693409/ https://ncbi.nlm.nih.gov/pubmed/18191465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.12.008 |
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