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Kinetic analysis of acetylation-dependent Pb1 bromodomain-histone interactions

Stopped-flow fluorescence anisotropy was used to determine the kinetic parameters that define acetylation-dependent bromodomain-histone interactions. Bromodomains are acetyllysine binding motifs found in many chromatin associated proteins. Individual bromodomains were derived from the polybromo-1 pr...

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Detalhes bibliográficos
Main Authors: Kupitz, Christopher, Chandrasekaran, Renu, Thompson, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519241/
https://ncbi.nlm.nih.gov/pubmed/18508185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2008.03.011
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