Rare HLA Drive Additional HIV Evolution Compared to More Frequent Alleles

HIV-1 can evolve HLA-specific escape variants in response to HLA-mediated cellular immunity. HLA alleles that are common in the host population may increase the frequency of such escape variants at the population level. When loss of viral fitness is caused by immune escape variation, these variants...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Rousseau, Christine M., Lockhart, David W., Listgarten, Jennifer, Maley, Stephen N., Kadie, Carl, Learn, Gerald H., Nickle, David C., Heckerman, David E., Deng, Wenjie, Brander, Christian, Ndung'u, Thumbi, Coovadia, Hoosen, Goulder, Philip J.R., Korber, Bette T., Walker, Bruce D., Mullins, James I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2009
Onderwerpen:
Pathogenesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693345/
https://ncbi.nlm.nih.gov/pubmed/19327049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2008.0208
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items