Additive Contribution of HLA Class I Alleles in the Immune Control of HIV-1 Infection

Previous studies have identified a central role for HLA-B alleles in influencing control of HIV infection. An alternative possibility is that a small number of HLA-B alleles may have a very strong impact on HIV disease outcome, dominating the contribution of other HLA alleles. Here, we find that eve...

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Autors principals: Leslie, Alasdair, Matthews, Philippa C., Listgarten, Jennifer, Carlson, Jonathan M., Kadie, Carl, Ndung'u, Thumbi, Brander, Christian, Coovadia, Hoosen, Walker, Bruce D., Heckerman, David, Goulder, Philip J. R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937780/
https://ncbi.nlm.nih.gov/pubmed/20660184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00320-10
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