The Amyloid β-Protein: Experiment and Theory on the 21-30 Fragment

The structure of the 21-30 fragment of the amyloid β-protein (Aβ) was investigated by ion-mobility mass spectrometry and replica exchange dynamics simulations. Mutations associated with familial Alzheimer’s disease (E22G, E22Q, E22K, and D23N) of Aβ(21-30) were also studied, in order to understand a...

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Hauptverfasser: Murray, Megan M, Krone, Mary Griffin, Bernstein, Summer L., Baumketner, Andrij, Condron, Margaret M., Lazo, Noel D., Teplow, David B., Wyttenbach, Thomas, Shea, Joan-Emma, Bowers, Michael T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693341/
https://ncbi.nlm.nih.gov/pubmed/19341254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp808384x
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