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Single Nucleotide Variants of the TGACTCA Motif Modulate Energetics and Orientation of Binding of the Jun-Fos Heterodimeric Transcription Factor

The Jun-Fos heterodimeric transcription factor is the terminal link between the transfer of extracellular information in the form of growth factors and cytokines to the site of DNA transcription within the nucleus in a wide variety of cellular processes central to health and disease. Here, using iso...

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Detalhes bibliográficos
Main Authors: Seldeen, Kenneth L., McDonald, Caleb B., Deegan, Brian J., Farooq, Amjad
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693225/
https://ncbi.nlm.nih.gov/pubmed/19215067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802068s
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