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Evidence that the bZIP Domains of the Jun Transcription Factor Bind to DNA as Monomers Prior to Folding and Homodimerization

The Jun oncoprotein belongs to the AP1 family of transcription factors that is collectively engaged in diverse cellular processes by virtue of their ability to bind to the promoters of a wide spectrum of genes in a DNA sequence-dependent manner. Here, using isothermal titration calorimetry, we repor...

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Detalhes bibliográficos
Main Authors: Seldeen, Kenneth L., McDonald, Caleb B., Deegan, Brian J., Farooq, Amjad
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597728/
https://ncbi.nlm.nih.gov/pubmed/18940179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.10.010
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