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Genetic Variations within the ERE Motif Modulate Plasticity and Energetics of Binding of DNA to the ERα Nuclear Receptor
Upon binding to estrogens, the ERα nuclear receptor acts as a transcription factor and mediates a multitude of cellular functions central to health and disease. Herein, using isothermal titration calorimetry (ITC) and circular dichroism (CD) in conjunction with molecular modeling (MM), we analyze th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044919/ https://ncbi.nlm.nih.gov/pubmed/21216218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.01.002 |
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