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Regulation of Pancreatic Tumor Cell Proliferation and Chemoresistance by the Histone Methyltransferase EZH2
PURPOSE: Enhancer of zeste homologue 2 (EZH2), a histone methyltransferase, plays a key role in transcriptional repression through chromatin remodeling. Our objective was to determine the expression pattern of EZH2 and assess the anticancer effect of EZH2 depletion in pancreatic cancer cells. EXPERI...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2690708/ https://ncbi.nlm.nih.gov/pubmed/18980972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1013 |
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