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Symphony of epigenetic and metabolic regulation—interaction between the histone methyltransferase EZH2 and metabolism of tumor

Increasing evidence has suggested that epigenetic and metabolic alterations in cancer cells are highly intertwined. As the master epigenetic regulator, enhancer of zeste homolog 2 (EZH2) suppresses gene transcription mainly by catalyzing the trimethylation of histone H3 at lysine 27 (H3K27me3) and e...

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Dades bibliogràfiques
Publicat a:Clin Epigenetics
Autors principals: Zhang, Tengrui, Gong, Yueqing, Meng, Hui, Li, Chen, Xue, Lixiang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245796/
https://ncbi.nlm.nih.gov/pubmed/32448308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00862-0
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