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Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance
The multidrug resistance 1 gene (MDR1) encodes P-glycoprotein (Pgp), a member of the ATP-binding cassette (ABC) transporter family that confers tumor drug resistance by actively effluxing a number of anti-tumor agents. We have previously shown that MDR1 transcription is regulated by epigenetic event...
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| Publicado en: | Cancer Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5675022/ https://ncbi.nlm.nih.gov/pubmed/20861184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0755 |
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