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Histone methyltransferase MLL3 contributes to genome-scale circadian transcription

Daily cyclical expression of thousands of genes in tissues such as the liver is orchestrated by the molecular circadian clock, the disruption of which is implicated in metabolic disorders and cancer. Although we understand much about the circadian transcription factors that can switch gene expressio...

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Détails bibliographiques
Auteurs principaux: Valekunja, Utham K., Edgar, Rachel S., Oklejewicz, Malgorzata, van der Horst, Gijsbertus T. J., O’Neill, John S., Tamanini, Filippo, Turner, Daniel J., Reddy, Akhilesh B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557088/
https://ncbi.nlm.nih.gov/pubmed/23297224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214168110
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