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The histone methyltransferase MLL1 permits the oscillation of circadian gene expression

The classical view of the molecular clock is based on interlocked transcriptional-translational feedback loops. Since a substantial fraction of the mammalian genome is expressed in a circadian manner, chromatin remodelling has been proposed to play a critical role in clock function. Here, we show th...

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Publicat a:Nat Struct Mol Biol
Autors principals: Katada, Sayako, Sassone-Corsi, Paolo
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501791/
https://ncbi.nlm.nih.gov/pubmed/21113167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1961
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