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Renal and Brain Isoforms of WNK3 Have Opposite Effects on NCCT Expression
Mutations in the WNK kinases WNK1 and WNK4 cause a rare familial form of hypertension (Gordon syndrome) by increasing expression of the thiazide-sensitive co-transporter NCCT in the kidney. Regulation of NCCT expression involves a scaffold of proteins composed of several kinases, including the third...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689907/ https://ncbi.nlm.nih.gov/pubmed/19470686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008050542 |
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