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A Single Amino Acid Substitution Makes WNK4 Susceptible to SB 203580 and SB 202190
Regulation of the SLC12 family of membrane transporters including NCCT involves a scaffold of interacting proteins including the STE 20 kinase SPAK and the WNK kinases, WNK 1 and WNK 4, which are mutated in the hypertensive syndrome of pseudohypoaldosteronism type 2 (PHAII). WNK4 regulates NCCT by a...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Open
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023092/ https://ncbi.nlm.nih.gov/pubmed/21249167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874104501004010057 |
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