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Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190

Small-molecule inhibitors of protein kinases have contributed immensely to our understanding of biological signaling pathways and have been exploited therapeutically for the treatment of cancers and other disease states. The pyridinyl imidazole compounds SB 203580 and SB 202190 were identified as AT...

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Détails bibliographiques
Publié dans:BMB Rep
Auteurs principaux: Shanware, Naval P., Williams, Leah M., Bowler, Michael J., Tibbetts, Randal S.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412876/
https://ncbi.nlm.nih.gov/pubmed/19336000
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