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Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190

Small-molecule inhibitors of protein kinases have contributed immensely to our understanding of biological signaling pathways and have been exploited therapeutically for the treatment of cancers and other disease states. The pyridinyl imidazole compounds SB 203580 and SB 202190 were identified as AT...

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Detalhes bibliográficos
Publicado no:BMB Rep
Main Authors: Shanware, Naval P., Williams, Leah M., Bowler, Michael J., Tibbetts, Randal S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412876/
https://ncbi.nlm.nih.gov/pubmed/19336000
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