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In vitro modeling of COPD inflammation and limitation of p38 inhibitor – SB203580

BACKGROUND: Systemic inflammation and steroid resistance are the hallmarks of COPD. We examined the impact of p38 inhibitor (SB203580) in in vitro assays of systemic inflammation using pulmonary cells and patients’ sera. OBJECTIVE AND METHODS: Data from 66 COPD patients and 15 age-/sex-matched healt...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Meng, Aihong, Zhang, Xiaopeng, Wu, Siyu, Wu, Mingxia, Li, Jing, Yan, Xixin, Kopec-Harding, Kamilla, Wu, Jiakai
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857829/
https://ncbi.nlm.nih.gov/pubmed/27199554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S99810
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