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Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190

Small-molecule inhibitors of protein kinases have contributed immensely to our understanding of biological signaling pathways and have been exploited therapeutically for the treatment of cancers and other disease states. The pyridinyl imidazole compounds SB 203580 and SB 202190 were identified as AT...

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Bibliografiske detaljer
Udgivet i:BMB Rep
Main Authors: Shanware, Naval P., Williams, Leah M., Bowler, Michael J., Tibbetts, Randal S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412876/
https://ncbi.nlm.nih.gov/pubmed/19336000
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