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WNK1 kinase isoform switch regulates renal potassium excretion

Members of the WNK family of serine/threonine kinases have been implicated as important modulators of salt homeostasis, regulating the balance between renal sodium reabsorption and potassium excretion. Gain-of-expression mutations in the WNK1 gene uncouple Na(+) and K(+) balance and cause a familial...

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Detalhes bibliográficos
Main Authors: Wade, James B., Fang, Liang, Liu, Jie, Li, Dimin, Yang, Chao-Ling, Subramanya, Arohan R., Maouyo, Djikolngar, Mason, Amanda, Ellison, David H., Welling, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482529/
https://ncbi.nlm.nih.gov/pubmed/16709664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603109103
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