Motor Mechanism for Protein Threading through Hsp104

The protein-remodeling machine Hsp104 dissolves amorphous aggregates as well as ordered amyloid assemblies such as yeast prions. Force generation originates from a tandem AAA+ (ATPases associated with various cellular activities) cassette, but the mechanism and allostery of this action remain to be...

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Bibliografiske detaljer
Main Authors: Wendler, Petra, Shorter, James, Snead, David, Plisson, Celia, Clare, Daniel K., Lindquist, Susan, Saibil, Helen R.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689388/
https://ncbi.nlm.nih.gov/pubmed/19362537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.02.026
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