Llwytho...

Cyclic Pyrrole-Imidazole Polyamides Targeted to the Androgen Response Element

Hairpin pyrrole-imidazole polyamides are a class of cell-permeable DNA-binding small molecules that can disrupt transcription factor-DNA binding and regulate endogenous gene expression. The covalent linkage of antiparallel Py-Im ring pairs with an γ-amino acid turn unit affords the classical hairpin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chenoweth, David M., Harki, Daniel A., Phillips, John W., Dose, Christian, Dervan, Peter B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689155/
https://ncbi.nlm.nih.gov/pubmed/19413319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja901309z
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