The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL

The BCL6 transcriptional repressor is required for development of germinal center (GC) B cells and when expressed constitutively causes diffuse large B-cell lymphomas (DLBCLs). We examined genome-wide BCL6 promoter binding in GC B cells versus DLBCLs to better understand its function in these settin...

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Detalhes bibliográficos
Main Authors: Ci, Weimin, Polo, Jose M., Cerchietti, Leandro, Shaknovich, Rita, Wang, Ling, Yang, Shao Ning, Ye, Kenny, Farinha, Pedro, Horsman, Douglas E., Gascoyne, Randy D., Elemento, Olivier, Melnick, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689052/
https://ncbi.nlm.nih.gov/pubmed/19307668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-193037
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