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A Novel Mechanism Is Involved in Cationic Lipid-Mediated Functional siRNA Delivery

[Image: see text] A key challenge for therapeutic application of RNA interference is to efficiently deliver synthetic small interfering RNAs (siRNAs) into target cells that will lead to the knockdown of the target transcript (functional siRNA delivery). To facilitate rational development of nonviral...

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Autori principali: Lu, James J., Langer, Robert, Chen, Jianzhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2009
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688906/
https://ncbi.nlm.nih.gov/pubmed/19292453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900023v
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