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Non-viral siRNA delivery to the lung()

SiRNAs exert their biological effect by guiding the degradation of their cognate mRNA sequence, thereby shutting down the corresponding protein production (gene silencing by RNA interference or RNAi). Due to this property, siRNAs are emerging as promising therapeutic agents for the treatment of inhe...

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Bibliografiske detaljer
Udgivet i:Adv Drug Deliv Rev
Main Authors: Thomas, Mini, Lu, James J., Chen, Jianzhu, Klibanov, Alexander M.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier B.V. 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103292/
https://ncbi.nlm.nih.gov/pubmed/17459519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2007.03.003
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