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siRNA Delivery to the Lung: What’s New?

RNA interference (RNAi) has been thought of as the general answer to many unmet medical needs. After the first success stories, it soon became obvious that short interfering RNA (siRNA) is not suitable for systemic administration due to its poor pharmacokinetics. Therefore local administration route...

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Detalhes bibliográficos
Main Authors: Merkel, Olivia M., Rubinstein, Israel, Kissel, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160355/
https://ncbi.nlm.nih.gov/pubmed/24907426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2014.05.018
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