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siRNA Delivery to the Lung: What’s New?

RNA interference (RNAi) has been thought of as the general answer to many unmet medical needs. After the first success stories, it soon became obvious that short interfering RNA (siRNA) is not suitable for systemic administration due to its poor pharmacokinetics. Therefore local administration route...

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Bibliographic Details
Main Authors: Merkel, Olivia M., Rubinstein, Israel, Kissel, Thomas
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160355/
https://ncbi.nlm.nih.gov/pubmed/24907426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2014.05.018
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