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siRNA Delivery to the Lung: What’s New?

RNA interference (RNAi) has been thought of as the general answer to many unmet medical needs. After the first success stories, it soon became obvious that short interfering RNA (siRNA) is not suitable for systemic administration due to its poor pharmacokinetics. Therefore local administration route...

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Bibliografiske detaljer
Main Authors: Merkel, Olivia M., Rubinstein, Israel, Kissel, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160355/
https://ncbi.nlm.nih.gov/pubmed/24907426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2014.05.018
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