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siRNA Delivery to the Lung: What’s New?

RNA interference (RNAi) has been thought of as the general answer to many unmet medical needs. After the first success stories, it soon became obvious that short interfering RNA (siRNA) is not suitable for systemic administration due to its poor pharmacokinetics. Therefore local administration route...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Merkel, Olivia M., Rubinstein, Israel, Kissel, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160355/
https://ncbi.nlm.nih.gov/pubmed/24907426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2014.05.018
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