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siRNA Delivery to the Lung: What’s New?

RNA interference (RNAi) has been thought of as the general answer to many unmet medical needs. After the first success stories, it soon became obvious that short interfering RNA (siRNA) is not suitable for systemic administration due to its poor pharmacokinetics. Therefore local administration route...

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Detalles Bibliográficos
Autores principales: Merkel, Olivia M., Rubinstein, Israel, Kissel, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160355/
https://ncbi.nlm.nih.gov/pubmed/24907426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2014.05.018
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