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A Novel Mechanism Is Involved in Cationic Lipid-Mediated Functional siRNA Delivery

[Image: see text] A key challenge for therapeutic application of RNA interference is to efficiently deliver synthetic small interfering RNAs (siRNAs) into target cells that will lead to the knockdown of the target transcript (functional siRNA delivery). To facilitate rational development of nonviral...

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Detalles Bibliográficos
Autores principales: Lu, James J., Langer, Robert, Chen, Jianzhu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2009
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688906/
https://ncbi.nlm.nih.gov/pubmed/19292453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900023v
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