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G Protein βγ Subunits as Targets for Small Molecule Therapeutic Development

G proteins mediate the action of G protein coupled receptors (GPCRs), a major target of current pharmaceuticals and a major target of interest in future drug development. Most pharmaceutical interest has been in the development of selective GPCR agonists and antagonists that activate or inhibit spec...

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Detalhes bibliográficos
Main Authors: Smrcka, Alan V., Lehmann, David M., Dessal, Axel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688719/
https://ncbi.nlm.nih.gov/pubmed/18537559
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