Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein
We recently derived a CD4-independent virus from HIV-1/IIIB, termed IIIBx, which interacts directly with the chemokine receptor CXCR4 to infect cells. To address the underlying mechanism, a cloned Env from the IIIBx swarm (8x) was used to produce soluble gp120. 8x gp120 bound directly to cells expre...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10339592/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.11.6359 |
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