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Intracellular Localization of the ABCC Proteins of Leishmania and Their Role in Resistance to Antimonials

The ABCC subfamily of proteins is composed of nine members in Leishmania. We report that all of these proteins have an intracellular localization and that the overexpression of at least four members, ABCC3, ABCC4, ABCC5, and ABCC7, can confer resistance to antimonials, the first-line drug against Le...

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書誌詳細
主要な著者: Leprohon, Philippe, Légaré, Danielle, Ouellette, Marc
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687239/
https://ncbi.nlm.nih.gov/pubmed/19307364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01474-08
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