Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes

Antimonial compounds are the mainstay for the treatment of infections with the protozoan parasite Leishmania. We present our studies on Leishmania infantum amastigote parasites selected for resistance to potassium antimonyl tartrate [Sb(III)]. Inside macrophages, the Sb(III)-selected cells are cross...

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Detalhes bibliográficos
Main Authors: El Fadili, Karima, Messier, Nadine, Leprohon, Philippe, Roy, Gaétan, Guimond, Chantal, Trudel, Nathalie, Saravia, Nancy G., Papadopoulou, Barbara, Légaré, Danielle, Ouellette, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087671/
https://ncbi.nlm.nih.gov/pubmed/15855523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1988-1993.2005
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