Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes

Antimonial compounds are the mainstay for the treatment of infections with the protozoan parasite Leishmania. We present our studies on Leishmania infantum amastigote parasites selected for resistance to potassium antimonyl tartrate [Sb(III)]. Inside macrophages, the Sb(III)-selected cells are cross...

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Bibliographische Detailangaben
Hauptverfasser: El Fadili, Karima, Messier, Nadine, Leprohon, Philippe, Roy, Gaétan, Guimond, Chantal, Trudel, Nathalie, Saravia, Nancy G., Papadopoulou, Barbara, Légaré, Danielle, Ouellette, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087671/
https://ncbi.nlm.nih.gov/pubmed/15855523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1988-1993.2005
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