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MRPA-independent mechanisms of antimony resistance in Leishmania infantum

Control of both human and canine leishmaniasis is based on a very short list of chemotherapeutic agents, headed by antimonial derivatives (Sb). The utility of these molecules is severely threatened by high rates of drug resistance. The ABC transporter MRPA is one of the few key Sb resistance protein...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Parasitol Drugs Drug Resist
Prif Awduron: Douanne, Noélie, Wagner, Victoria, Roy, Gaetan, Leprohon, Philippe, Ouellette, Marc, Fernandez-Prada, Christopher
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225602/
https://ncbi.nlm.nih.gov/pubmed/32413766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2020.03.003
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