Arsenate Reductase, Mycothiol, and Mycoredoxin Concert Thiol/Disulfide Exchange

We identified the first enzymes that use mycothiol and mycoredoxin in a thiol/disulfide redox cascade. The enzymes are two arsenate reductases from Corynebacterium glutamicum (Cg_ArsC1 and Cg_ArsC2), which play a key role in the defense against arsenate. In vivo knockouts showed that the genes for C...

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Autors principals: Ordóñez, Efrén, Van Belle, Karolien, Roos, Goedele, De Galan, Sandra, Letek, Michal, Gil, Jose A., Wyns, Lode, Mateos, Luis M., Messens, Joris
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Enzyme Catalysis and Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685692/
https://ncbi.nlm.nih.gov/pubmed/19286650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900877200
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