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Mycothiol/Mycoredoxin 1-dependent Reduction of the Peroxiredoxin AhpE from Mycobacterium tuberculosis

Mycobacterium tuberculosis (M. tuberculosis), the pathogen responsible for tuberculosis, detoxifies cytotoxic peroxides produced by activated macrophages. M. tuberculosis expresses alkyl hydroxyperoxide reductase E (AhpE), among other peroxiredoxins. So far the system that reduces AhpE was not known...

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Detalhes bibliográficos
Main Authors: Hugo, Martín, Van Laer, Koen, Reyes, Aníbal M., Vertommen, Didier, Messens, Joris, Radi, Rafael, Trujillo, Madia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931079/
https://ncbi.nlm.nih.gov/pubmed/24379404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.510248
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