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How Thioredoxin Dissociates Its Mixed Disulfide

The dissociation mechanism of the thioredoxin (Trx) mixed disulfide complexes is unknown and has been debated for more than twenty years. Specifically, opposing arguments for the activation of the nucleophilic cysteine as a thiolate during the dissociation of the complex have been put forward. As a...

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Hlavní autoři: Roos, Goedele, Foloppe, Nicolas, Van Laer, Koen, Wyns, Lode, Nilsson, Lennart, Geerlings, Paul, Messens, Joris
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714181/
https://ncbi.nlm.nih.gov/pubmed/19675666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000461
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