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Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli

The crystal structure of Escherichia coli ribonuclease I (EcRNase I) reveals an RNase T2-type fold consisting of a conserved core of six β-strands and three α-helices. The overall architecture of the catalytic residues is very similar to the plant and fungal RNase T2 family members, but the perimete...

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Detalhes bibliográficos
Main Authors: Rodriguez, Sergio Martinez, Panjikar, Santosh, Van Belle, Karolien, Wyns, Lode, Messens, Joris, Loris, Remy
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271172/
https://ncbi.nlm.nih.gov/pubmed/18305191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073420708
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