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Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

The envelope glycoprotein of human immunodeficiency virus (HIV) consists of an exterior glycoprotein (gp120) and a trans-membrane domain (gp41) and has an important role in viral entry into cells. HIV-1 entry has been validated as a clinically relevant anti-viral strategy for drug discovery. In the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zhou, Jiehua, Swiderski, Piotr, Li, Haitang, Zhang, Jane, Neff, C. Preston, Akkina, Ramesh, Rossi, John J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2009
נושאים:
RNA
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685106/
https://ncbi.nlm.nih.gov/pubmed/19304999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp185
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