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Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

The envelope glycoprotein of human immunodeficiency virus (HIV) consists of an exterior glycoprotein (gp120) and a trans-membrane domain (gp41) and has an important role in viral entry into cells. HIV-1 entry has been validated as a clinically relevant anti-viral strategy for drug discovery. In the...

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Bibliografski detalji
Glavni autori: Zhou, Jiehua, Swiderski, Piotr, Li, Haitang, Zhang, Jane, Neff, C. Preston, Akkina, Ramesh, Rossi, John J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685106/
https://ncbi.nlm.nih.gov/pubmed/19304999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp185
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