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Novel Dual Inhibitory Function Aptamer–siRNA Delivery System for HIV-1 Therapy

The successful use of small interfering RNAs (siRNAs) for therapeutic purposes requires safe and efficient delivery to specific cells and tissues. In this study, we demonstrate cell type–specific delivery of anti-human immunodeficiency virus (anti-HIV) siRNAs through fusion to an anti-gp120 aptamer....

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Detalles Bibliográficos
Main Authors: Zhou, Jiehua, Li, Haitang, Li, Shirley, Zaia, John, Rossi, John J
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727148/
https://ncbi.nlm.nih.gov/pubmed/18461053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.92
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