The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing

Proteins of the GW182 family interact with Argonaute proteins and are required for miRNA-mediated gene silencing. These proteins contain two structural domains, an ubiquitin-associated (UBA) domain and an RNA recognition motif (RRM), embedded in regions predicted to be unstructured. The structure of...

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Bibliografiske detaljer
Main Authors: Eulalio, Ana, Tritschler, Felix, Büttner, Regina, Weichenrieder, Oliver, Izaurralde, Elisa, Truffault, Vincent
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685099/
https://ncbi.nlm.nih.gov/pubmed/19295135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp173
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